FlowMedica公司开发出防止肾功能不全的设备

 
一种新型设备被设计用于防止充血性心衰患者在接受冠状动脉手术的时候出现肾功能不全。

慢性肾脏疾病合并充血性心衰会增加由于血管造影术中使用的染料或者支架手术时候发生肾脏功能衰竭的危险。这套Benephit Delta系统是以导管为基础的医疗设备，能够将特定药物和其它治疗药物直接输送到肾动脉。系统能够对两根肾动脉同时进行选择性给药，而只需使用一根导管。设计这套系统的主要目的是进行靶向肾脏治疗，作为系统性静脉注射药物治疗充血性心衰相关肾脏功能不全的替代选择。

近期在美国NewYork-Presbyterian医院一例男性患者中进行了这种操作程序，该患者当时接受血管扩张手术以治疗冠状动脉重度阻塞。在他的冠状动脉中放置了5个支架，这需要使用大剂量的染料。手术中使用Benephit Delta系统将一种药物 (非诺多泮)通过肾脏动脉直接输送到患者的肾脏，以增加血流量。患者没有出现危及生命的放射造影剂肾病。心血管医生估计大约有20％接受冠状动脉干预手术的患者能够从对放射造影剂肾病的治疗中获益。

Benefit Delta系统是由美国FlowMedica公司研制开发的，这是一家医疗设备公司。

Device Helps Prevent Kidney Dysfunction
 
A new device is designed to help prevent kidney dysfunction in patients with congestive heart failure (CHF) while undergoing coronary procedures.

The combination of chronic kidney disease and CHF greatly increases a patient’s risk of developing kidney failure from the dye used during an angiography or stenting procedure. The Benephit Delta system is a catheter-based medical device that enables the administration of specified medications and other therapeutic agents directly to the renal arteries. The system can provide selective infusion to both renal arteries simultaneously, using a single catheter. It is designed to provide targeted renal therapy (TRT), an alternative to systemic intravenous infusion of medications to treat kidney dysfunction related to CHF.

The procedure was recently used on a male patient at NewYork-Presbyterian Hospital (NY, USA) who had recently had angioplasty to treat two severely blocked coronary arteries. Five stents were placed in his coronary arteries, which required large amounts of dye. The Benephit Delta system was used to deliver a medication (fenoldopam) directly into the patient’s kidneys through the renal arteries to increase blood flow. The patient did not develop the potentially life-threatening condition known as radiocontrast nephropathy (RCN). Cardiologists estimate that about 20% of patients undergoing coronary interventions could benefit from treatment for RCN.

The Benefit Delta system was developed by FlowMedica, a medical device company (Fremont, CA, USA).