Nanogen公司开发出呼吸道病毒检测的新型试剂

 
 
一种多元固相杂交试剂被开发用于在流感高发季节里检测6种呼吸道病毒流行情况。

这种特异性分析试剂(ASR)叫做NGEN RVA，可以用于A型和B型流感病毒、呼吸道合胞病毒、副流感病毒1、2、3型的序列和鉴别。这种检测能够在不同样本中进行，包括鼻拭子，可以作为临床检测方法。还包括进行科研使用的实时定量PCR试剂探针和引物，可以用于鉴别A型和B型流感病毒。

这些试剂由Nanogen公司(San Diego, CA, USA)提供，是和Prodesse公司(Waukesha, WI, USA)合作共同开发的，这是一家感染性疾病分子诊断试剂的权威供应商。这些试剂已经获得了CE标记。

这些试剂针对的核酸序列同样在H5N1型流感病毒株中发现，也被叫做禽流感病毒。对禽流感病毒筛查感兴趣的实验室可以选择实时定量PCR试剂，或者被批准用于临床诊断的ASRs试剂。

Diagnostics for Respiratory Pathogens
 
A multiplex solid-phase hybridization set of reagents can be used to develop and validate assays for the detection of the sequences of six human respiratory viruses prevalent during the flu season.

The analyte-specific reagents (ASR), called NGEN RVA, can be used to develop assays that can detect the sequences of, and differentiate among, influenza A and B, respiratory syncytial virus, and parainfluenza 1, 2, and 3. The assays can be performed with various sample types, including nasal swabs, and can be used as clinical diagnostic tests. Included with the reagents are a research-use-only real-time polymerase chain reaction (PCR) probe and primer for the identification of the influenza A and B viruses.

The reagents, available from Nanogen, Inc. (San Diego, CA, USA), were developed in cooperation with Prodesse, Inc. (Waukesha, WI, USA), a leading supplier of molecular-based reagents for infectious diseases. The reagents have received the CE Mark.

The reagents target a nucleic acid sequence also found in the H5N1 strain of the influenza, known as the avian flu virus. Labs interested in screening for avian flu can choose between the real-time PCR research reagents or the set of ASRs that can be validated for clinical use.