非创伤性通气治疗有利于高碳酸血症患者

根据一项最新研究发现，早期应用非创伤性通气治疗拔管后的呼吸衰竭，降低了重症监护室高危患者的死亡率。

一项前瞻性随机对照临床试验包括了162例使用机械通气的患者，在急性高碳酸血症康复之后，患者能够耐受自主呼吸试验，但是在拔管后出现呼吸衰竭的危险增加。患者在拔管之后被随机分配接受非创伤性正压通气(NPPV)24小时，或者传统的氧气治疗。

最后研究人员得出结论，非创伤性通气能够有利于提高出现慢性呼吸性高碳酸血症患者的生存率，可以开展新的前瞻性临床试验。
 
 
Noninvasive Ventilation in Hypercapnic Patients
 
Early use of noninvasive ventilation averted respiratory failure after extubation and decreased intensive care unit mortality among patients at increased risk, a new study has found.

A prospective randomized controlled trial was conducted in 162 mechanically ventilated patients who tolerated a spontaneous breathing trial after recovery from an acute hypercapnic respiratory failure episode, but had increased risk for respiratory failure after extubation. Patients were randomly allocated after extubation to receive noninvasive positive pressure ventilation (NPPV) for 24 hours or conventional management with oxygen therapy.

The researchers concluded that the beneficial effect of noninvasive ventilation in improving survival of hypercapnic patients with chronic respiratory disorders warrants a new prospective clinical trial.