意大利科学家发现替米沙坦控制血压的效果优于其他药物

 
一项最新荟萃分析研究显示：与其他先进得血管紧张素II拮抗剂相比，在降低清晨血压方面，替米沙坦的效果明显占据优势。

Milano-Bicocca大学(Italy)的研究人员对11项临床研究中5100例轻度－中度高血压患者的资料进行了汇总分析。24小时动态血压监测(ABPM)被用于监测血压下降程度的波动，并用于计算替米沙坦和其他常用抗高血压药物的平滑指数(SI)，包括缬沙坦、洛沙坦、雷米普利和氨氯地平。平滑指数是预防器官损伤的有效指标，定义为由于治疗引起的24小时血压变化平均值，除以相应的标准差。较高的SI指数代表血压下降平稳而明显。
 
Telmisartan Better at Controlling Blood Pressure
  
A new meta-study shows that telmisartan provides superior, powerful blood pressure
reduction from morning to morning compared to other leading angiotensin II blockers.

Researchers from the University of Milano-Bicocca (Italy) examined a pooled analysis of over 5,100 patients with mild-to-moderate hypertension in 11 studies. Ambulatory blood pressure monitoring (ABPM) readings over 24 hours were used to measure fluctuations in blood pressure reductions and to calculate smoothness index (SI) scores for telmisartan and other commonly used antihypertensives, including valsartan, losartan, ramipril, and amlodipine. The smoothness index, a potential indicator for the prevention of organ damage, is defined as the average of the 24 hourly blood pressure changes induced by treatment, divided by the corresponding standard deviation. A high SI score represents a blood pressure reduction that is meaningful and smooth.