Accumetrics开发出阿司匹林是否有效的检测方法

VerifyNow检测是一种快速阿司匹林血液检测方法，有助于鉴别服用阿司匹林，但是没有完全获得对心脏病发作和脑中风保护性作用的患者。这种检测已经获得了美国食品药品管理局签发的自动弃权许可，免除了该检测只能够在中等复杂实验室进行操作的要求。

VerifyNow检测方法是由Accumetrics公司(San Diego, CA, USA)研制开发的，是第一个获得这种自动弃权许可的血小板功能试验。这种检查能够很快得到一个简单的数值，该结果能够提示患者对阿司匹林有反应以及十分得到了充分保护，或者提示患者对阿司匹林没有反应，从而患者患心血管疾病的危险增加。如果发现患者是无反应的，就需要增加剂量，调整同时使用的干扰阿司匹林效果的其它药物，或者使用另外类型的抗血小板药物。越来越多的证据显示，多达30%每日使用阿司匹林期望获得保护作用的患者对阿司匹林没有足够的反应。

美国普罗维登斯Saint Joseph医院心血管医生Mar Ladenheim说：“使用这种简单的测试方法，患者能够平静地离开医生诊室，因为他们已经知道阿司匹林是否对他们起作用。或者他们是属于那些没有反应地患者，这就给了患者与医生调整治疗的机会，从而不会耽误病情。”
 
Test for Aspirin Effectiveness
 
The VerifyNow aspirin test is a rapid blood test that helps to identify patients taking aspirin who are not receiving the full benefits of its protective effects against heart attack and stroke. The test has been granted a waiver by the U.S. Food and Drug Administration (FDA) eliminating the requirement that the test be performed only in moderately complex laboratories.

The VerifyNow test, developed by Accumetrics (San Diego, CA, USA), is the first platelet function assay to receive this waiver. The test provides a rapid result with one simple number indicating if a patient is responding to aspirin and adequately protected, or is unresponsive to aspirin and thus at increased risk for cardiovascular risks. If a patient is found to be nonresponsive, the dosage may need to be increased, the use of other drugs that can interfere with aspirin’s effect may need to be modified, or the use of another type of antiplatelet agent may be indicated. There is growing evidence that up to 30% of patients taking a daily aspirin for its protective effects do not fully respond to aspirin.

“With this one simple test, patients can leave the doctor’s office with the peace of mind of knowing that aspirin is working for them,” said Mar Ladenheim, M.D., a cardiologist at Providence Saint Joseph Hospital (Los Angeles, CA, USA). “Or if they’re among those who aren’t responding, this gives them the opportunity to work with their physician to modify treatment before it’s too late.”