CryoLife公司提供用于膝关节移植手术的低温保存组织

在一次整形外科手术中，灭活抗原保护剂处理过的低温保存的整形外科组织，被移植入患者体内。

这种低温保存的整形外科组织来自CryoLife公司，该公司在心血管和血管外科手术中使用的活体移植组织的处理和销售方面处于领导地位。为了确保该公司组织的安全性，CryoLife获得了Clearant集团的Clerant处理许可。这种技术使用伽马射线以及放射灭活方法来灭活抗原，包括微生物，而同时能够维持组织的完整性。使用这种处理技术确保了血液制品、血浆制品以及组织移植物的安全性。

在整形外科手术中，一旦整形组织使用了Clearant方法处理，就可以被移植入患者体内重建患者膝盖的前十字韧带以及后十字韧带。在该例患者，使用两个胫腓骨肌腱替代患者被损害的前十字韧带和后十字韧带。

CryoLife公司计划使用Clearant处理方案为外科医生提供低温保存的膝盖骨、胫腓骨、四头肌以及腓骨肌腱。David Caborn医生在Jewish医院进行了该手术，他说：“我已经为CryoLife公司工作了好几年，从事的项目是使用低温保存肌肉骨骼组织，重建失去稳定性以及疼痛的膝关节。Clearant处理方案为外科医生提供了使用放射处理的整形组织，在灭活病原的同时，这种组织的强度以及结构特征没有受到损害。”
 
Treated Cryopreserved Tissues Implanted in Knee
 
Cryopreserved orthopedic tissues treated with a protectant that inactivates pathogens have been implanted in a patient undergoing orthopedic surgery.

The cryopreserved orthopedic tissues were from CryoLife, Inc. (Atlanta, GA, USA), a leader in the processing and distribution of implantable living human tissues for use in cardiovascular and vascular surgeries. To ensure the safety of its tissues, CryoLife has licensed the Clearant Process from Clearant, Inc. (Los Angeles, CA, USA). This technology uses gamma irradiation and a dioprotectant to inactivate pathogens, including microorganisms, while maintaining tissue integrity. The process is used to ensure the safety of blood products, plasma therapies, and tissue allograft implants.

In the orthopedic procedure, once the orthopedic tissues were treated by the Clearant process, they were implanted in a patient to reconstruct the anterior cruciate ligament (ACL) and the posterior cruciate ligament (PCL) in the patient’s knee. In this case, two tibialis tendons were used to replace the patient’s damaged ACL and PCL. CryoLife plans to make available cryopreserved patellar, tibialis, Achilles, quadriceps, and peroneus tendons treated with the Clearant process to orthopedic surgeons.

“I have worked with CryoLife for several years transplanting their yopreserved musculoskeletal tissues to reconstruct painful, unstable knees,” said Dr. David Caborn, who performed the surgery at Jewish Hospital (Louisville, KY, USA). “The Clearant process provides surgeons with the opportunity to use irradiated orthopedic tissue without compromising the tissue’s strength and structural properties, while inactivating pathogens.”