妊娠妇女尿酸增高会增加发生并发症的危险

 
根据2005年10月27日《高血压在线》的报道，患高血压的妊娠妇女血液中尿酸水平升高，会增加母亲与胎儿患上危及生命的并发症。

美国匹兹堡大学(PA, USA)的研究人员使用数据库来寻找先兆子痫患者的尿酸水平，是否有助于发现妊娠妇女并发症升高的危险。他们检查了匹兹堡大学Magee妇女医院972例患进行性子痫妊娠妇女的医疗记录。

研究人员发现先兆子痫而且尿酸水平升高的女性，早产的危险增加了7倍之多，几乎比尿酸水平正常的先兆子痫女性分娩期要提前4周。绝大多数分娩都是诱导的而且婴儿出生时候体积都较小。但是在患高血压患者尿液中没有蛋白质但是尿酸增高的女性，早产或者胎儿存活下降的危险与出现经典先兆子痫症状但是尿酸正常的女性相似。高血压患者尿液中没有蛋白质而且尿酸正常的患者，她们婴儿的危险并不增加。

Uric Acid May Threaten Pregnancy
 
Pregnant women with hypertension who also have elevated levels of uric acid in their blood may have an increased risk of complications that could be fatal for both mother and baby, according to a study reported in the October 27, 2005, online issue of Hypertension.

Researchers at the University of Pittsburgh (PA, USA) used a research database to find whether inclusion of uric acid levels in the diagnosis of preeclampsia would help them evaluate the risk for complications among pregnant women. They looked at the records for 972 pregnant women who were part of an ongoing preeclampsia study at the Magee-Women’s Hospital of the University of Pittsburgh.

They found that women with both preeclampsia and elevated uric acid levels had almost a seven-fold increased risk of premature delivery and delivered nearly four weeks earlier than preeclampsia women whose uric acid levels were normal. Most of these deliveries were induced and infants tended to be smaller at birth. However, in women with high blood pressure and no protein in their urine but who did have increased uric acid, the risk of early delivery or reduced fetal growth was as likely as in women with classic signs of preelcampsia but normal uric acid. Also, women with high blood pressure who lacked protein in their urine and had normal uric acid had no increased risk for their babies.