闭合式输液系统能够降低感染的发生

 
与开放式系统相比较，一种闭合式中央静脉输液系统，能够降低超过一半的导管相关性血液感染。

这是一项1012例重症监护室内使用中央静脉导管的患者的评估结果。这项研究入选的是巴西3家三级护理重症监护室的患者，这些患者放置了中央静脉导管至少24小时。在开放阶段感染率，每1,000例中央静脉导管日是7.1，而闭合阶段是3.2。研究人员得出结论与开放式系统相比较，闭合式中央静脉导管感染的危险下降了一半多。

这些研究结果在2005年12月美国华盛顿举行的第45届抗微生物和化学治疗交叉学科年会上进行了报道。

研究人员计算了两个时间阶段的导管相关性血液感染率。在主动检测阶段，医院使用一种开放式系统，这种系统是半刚性塑料瓶，有一个端口能够外接半刚性塑料瓶。在第二阶段，医院则使用一种闭合式系统，这种系统由项圈式塑料袋组成，具有两个端口但是没有出口。

Closed Infusion System Reduces Infection
 
A closed central intravenous infusion system can cut by more than half the rate of catheter-associated bloodstream infection compared to an open system.

These were the results of a study that evaluated 1,012 intensive care unit (ICU) patients with central venous catheters. The trial enrolled adults admitted to three tertiary-care ICUs in Brazil who had a central venous catheter in place for at least 24 hours. Rates of infection per 1,000 central venous catheter days were 7.1 during the open phase and 3.2 during the closed phase. The researchers concluded that the risk for getting central venous catheter infection was more than half that of the closed system than with the open system.

These findings were presented at the 45th annual Interscience Conference on Antimicrobial Agents and Chemotherapy, held in December 2005 in Washington (DC, USA).

The investigators calculated the rates of catheter-associated bloodstream infection during two time periods. In the active surveillance phase, the hospital used an open system, characterized by semi-rigid plastic bottles that had one port and were externally vented semi-rigid plastic bottles. In the second phase, the hospital switched to a closed system, which consisted of collapsible plastic bags that had two ports and were not vented.