UPMC发现肥胖患者血压随着体重下降而下降

 
一项最新研究发现，重度肥胖患者在接受胃旁路手术之后，血压出现了显著而长期的改善。

Pittsburgh大学医学中心(UPMC, Pennsylvania, USA)体重控制中心的研究人员，分析了347例肥胖患者的资料，这些患者起始的体重指数(BMI)大于40，在1992～2001年期间在UPMC接受了胃旁路手术治疗。半数的患者在接受手术之前被诊断为高血压，但是只有少数患者接受过抗高血压治疗。在进行资料分析的时候，也就是在手术后18个月，他们的BMIs稳定在35左右，仍然属于肥胖。

那些在手术之前没有接受过抗高血压的患者，血压出现了显著下降，至少持续至手术之后的18个月。那些在手术之前接受过积极的药物治疗的患者，大约有三分之一在手术之后减少了或者不再使用降压药物。那些血压正常的患者在手术之后血液变化则并不显著。这些研究结果发表在2006年3月《外科手术档案》之上。
 
Blood Pressure Drops Along With Weight
 
A new study finds that severely obese patients may experience significant, long-term improvements in blood pressure after gastric bypass surgery.

Researchers at the University of Pittsburgh Medical Center (UPMC, Pennsylvania, USA) Weight Management Center analyzed data from 347 obese patients, with an initial body mass index (BMI) greater than 40, who underwent gastric bypass surgery at UPMC between 1992 and 2001. Half of the study patients were diagnosed as hypertensive prior to surgery, but only some of them were being treated for their hypertension. At the time of data analysis, 18 months after surgery, their BMIs had stabilized to about 35, still categorized as obese.

The patients who were not being treated for hypertension prior to surgery experienced significant blood pressure decreases that continued to remain low 18 months after surgery. Of the patients under active drug treatment for hypertension prior to surgery, about one-third were able to reduce or eliminate their blood pressure medications after surgery. The group of patients with normal blood pressure showed insignificant changes following surgery. The results were published in the March 2006 issue of the Archives of Surgery.