英发现手术治疗子宫纤维瘤的效果优于栓塞治疗

 
一项最新研究发现，采用手术治疗症状性子宫纤维瘤，并发症要比栓塞治疗要少，但是平均住院时间较长。

Glasgow(UK)大学和爱丁堡大学医学院(UK)研究人员将子宫纤维瘤的妇女，按照2:1的比例随机分配，患者接受子宫动脉栓塞(UAE)治疗，也就是将纤维瘤的血液供应阻断，或者接受手术治疗，结果有106例接受UAE手术而51例接受手术治疗(43例子宫切除，8例肌神经切除)。这项研究的主要预后指标湿1年后随访的生命质量，通过问卷调查进行测量，即医疗预后研究36项短表格一般健康调查(SF-36)。

结果显示在1年之后，手术组的症状评分在总体上优于UAE组。在第1年13例UAE治疗妇女出现不良症状事件(12%)，而手术组有10例(20%)。10例UAE患者需要再次治疗，或者在此UAE治疗或者子宫切除。除此之外，在1年之后，UAE组中有14例(13%)需要在此入院，3例出现重大不良事件，11例由于初次UAE不成功而需要再次治疗。该研究结果发表在2007年1月25日的《新英格兰医学期刊》之上。

Surgery Versus Embolization in Treating Fibroids
 
A new study has found that surgery for the treatment of symptomatic uterine fibroids results in fewer complications than embolization, but requires on average a significantly longer hospital stay.

Researchers of the University of Glasgow (UK) and the University of Edinburgh Medical School (UK) randomly assigned women suffering from uterine fibroids in a 2:1 ratio to undergo either uterine-artery embolization (UAE)--where the blood supply to the fibroids is blocked--or surgery, with 106 patients undergoing UAE and 51 undergoing surgery (43 hysterectomies and eight myomectomies). The primary outcome of the study was quality of life at one year follow-up, as measured by a questionnaire known as the medical outcomes study 36-item short-form General Health Survey (SF-36).

The results showed that after 1 year, the symptom scores in the surgical group were on the whole better than the UAE group. Within the first year period 13 of the UAE women had adverse symptom events (12%) compared with 10 in the surgery group (20%). Ten of the UAE patients needed a repeat treatment, either another UAE or hysterectomy. Additionally, after the first year, 14 women in the UAE group (13%) needed to be re-admitted to hospital, three for major adverse events and 11 for repeat treatment because the original UAE had not been successful. The results are published in the January 25, 2007, edition from The New England Journal of Medicine.