颅外立体定向放射治疗可以减少肺癌患者的副作用

颅外立体定向放射治疗可以减少肺癌患者的副作用
    颅外立体定向放射疗法通常应用于颅内肿瘤，但今年来随着实时图象设备和光束整型设备的进步，它也开始广泛应用于身体的其他部位，这些进步包括On-Board Imager，一种从线型加速器扩展出的显像设备，以及高精度图象引导的放射法（IGRT），以及120叶Millennium多点传出瞄准仪，如果没有这些发展，医生不得不连同靶癌灶周围的5－10mm的健康组织切除掉。
    一名36岁的中年肺癌妇女患者成为瑞士第一位使用一种名叫颅外立体定向放射治疗的强定向型放射治疗的患者，外科手术对这位患者已经不适合了，因为她一年前已经切除了一半肺，残肺现在又发现癌灶，所以只能采用为期10天的三次高计量定向放射疗法(使用来自威瑞恩医疗体系（美国加州帕罗阿图市）的先进设备和来自瑞士波恩Lindenhofspital的一个临床医生团队进行了三次有效的高计量强放射治疗目的是为了破坏患者肺部的小癌灶)，令人欣慰的是患者对此疗法有反映。Leon Andre医生说病人现在癌灶已经缩小，病情正在恢复中，这次治疗使用的市威瑞恩的Clinac 23EX型带有120叶MLC多路传出瞄准仪的直线加速器，能使医生将光线调小到毫米级精度从而减小副作用。

Extra-Cranial Stereotactic Radiotherapy Lessens Side Effects for Lung Cancer Patients
    Stereotactic radiation therapy treatment is frequently used for cranial tumors but recent advances in real-time imaging equipment and beam-shaping devices have broadened its use to the rest of the body. These advances include the On-Board Imager, an imaging device that extends from the linear accelerator and enables highly accurate image-guided radiotherapy (IGRT) treatments, and the 120-leaf Millennium multileaf collimator, which allows the beam to be shaped to extreme levels of precision. Without such developments, clinicians would have been forced to expose a margin of between 5 and 10 mm of healthy tissue around the target tumor to account for possible movement.
    A 36-year-old female lung cancer patient has become the first person in Switzerland to be treated using a highly targeted radiotherapy technique called extra-cranial stereotactic radiotherapy. Surgery was not an option for this patient because her other lung had been removed a year ago,?explained Dr. Andre. new tumor appeared on her remaining lung and we decided that the best option would be to deliver three high-dose stereotactic treatments over a 10-day period.( Using advanced equipment from Varian Medical Systems (Palo Alto, CA, USA), a team of clinicians at Lindenhofspital (Bern, Switzerland) has effectively delivered three highly focused, powerful radiotherapy doses aimed at destroying a small tumor on the patient’s lung.) We are very pleased with the way the patient has responded to this new stereotactic treatment.?
    Dr. Leon Andre, a medical physicist at the private Lindenhofspital, reported the tumor has shrunk as a result of the treatment and the patient is now recovering well. The treatment took place using a Varian Clinac 23EX linear accelerator with a 120-leaf MLC (multileaf collimator) to enable clinicians to narrow down the beam to millimeter accuracy, thereby reducing the risk of side effects.