Acolyte公司推出MRSA快速检测方法

一种耐甲氧西林金黄色葡萄球菌（MRSA）的新型快速检测方法当日就可以出结果，允许感染控制小组能够快速做出反应从而防止医院获得性感染。

BacLite快速MRSA检测方法，是由Acolyte生物医学公司研制开发的。对该检测方法的最终评估正在3所英国实验室中进行，显示该检测方法能够在5小时之内完成，而目前使用的微生物学检测方法需要2天才能够得到结果。Acolyte生物医学公司首席执行官Bill Mullen博士说：“我们期望这种检测方法能够提在至关重要的时候供快速而价格低廉的筛查方法，有效的对抗MRSA。”

在一项多中心临床试验中，1377份鼻拭子的检测敏感性是93.4%而特异性是95.8%。阴性概率是正确的（阴性预测值）超过99%。

2005年6月《临床微生物感染》报道的资料显示：合适的筛查方案能够减少50%的MRSA。在该项试验中使用的严格的筛查方法是“寻找并摧毁”途径的坚实后盾，在荷兰得以成功的实行。在联合王国，床位占用率极高以及这种超级细菌的感染性极高的菌株，提示传统筛查方法速度太慢而不能发挥作用。一些英国医院正在越来越多的使用快速检测方法来迎接这种挑战。这种新型BacLike MRSA检测方法可以帮助他们所作出的努力。

Rapid Test for MRSA
 
A new, rapid test for methicillin-resistant staphylococcus aureus (MRSA) gives same-day results, allowing infection-control teams to act quickly to prevent the spread of hospital-acquired infection.

The BacLite rapid MRSA test was developed by Acolyte Biomedica Ltd. (Porton Down, UK). The final evaluation of the test was made at three UK laboratories and showed that the test can achieve in five hours what current microbiologic methods take two days to deliver. “We expect this test to offer a rapid and cost-effective screening method at an important time in the fight against MRSA,” said Dr. Bill Mullen, CEO of Acolyte Biomedica.

In a multicenter trial of 1,377 nasal swabs, the sensitivity of the test was 93.4% and specificity was 95.8%. The probability that a negative result was correct (negative predictive value) was more than 99%.

Data from a study reported in the June 2005 issue of Clinical Microbial Infections have shown that a properly implemented screening program can reduce MRSA by over 50%. The kind of rigorous surveillance used in the study is the backbone of the “seek and destroy” approach, so successfully used in The Netherlands. In the United Kingdom, the combination of high bed occupancy rates and very infectious strains of the superbug suggests that traditional screening methods may be too slow for maximum effect. Rapid testing is increasingly becoming the method used by some UK hospitals to meet the challenge. The new BacLike MRSA test is designed to aid their effort.