核心针孔穿刺基因表达谱检测诊断乳腺癌

 
根据一项最新研究发现，核心针孔穿刺诊断乳腺癌的基因表达谱检测，是肿瘤基因表达检测的一个代表，是乳腺癌诊断的一个可靠指标。

这项研究发表在2006年8月的《乳腺癌研究期刊》之上，验证了核心针孔穿刺活检作为乳腺癌诊断和预后手段的可靠性。该研究还显示核心针孔穿刺诊断乳腺癌，可能比穿刺之后从肿瘤上手术获取标本的精确性要高。根据这些研究结果，活检手术触发了与损伤修复相关的基因表达，从而改变了后续手术采集样本的基因表达谱。

 
Gene Expression in Core Needle Biopsy Diagnoses Breast Cancer
 
The gene-expression profile detected in a core needle biopsy of a breast tumor is representative of gene expression in the whole tumor and therefore a reliable diagnostic for breast cancer, according to a new study.

The study, published in the August 2006 edition of the journal Breast Cancer Research, confirms the reliability of core needle biopsy as a tool in breast-cancer diagnosis and prognosis. The study also shows that the gene expression profile of a core needle biopsy might be more accurate than the profile of a surgical sample taken from the same tumor after the biopsy was carried out. According to the study results, the biopsy procedure triggers the expression of genes involved in wound healing as well as tumor invasion and metastasis, thus modifying the gene expression profile of subsequent surgical samples.