Dade Behring公司改进细菌敏感性检测方法

一种改良规划设计被开发用于MicroScan干燥革兰氏阳性过夜抗微生物易感性检测面板。这种新的改良规划设计已经获得了美国食品药品管理局的许可。

由于金黄色葡萄球菌耐药性不断增加，Dade Behring现在供应的这种自动化系统改进了对耐万古霉素金黄色葡萄球菌的检测。

Dade Behring公司MicroScan临床与科学事务部主任Barbara Zimmer博士解释说：“我们的研究团队知道这对临床医生和他们的患者而言是多么的重要；我们了解万古霉素是一个十分重要的抗菌药，在治疗耐甲氧西林和其他抗生素的金黄色葡萄球菌方面发挥着重要作用。”

根据美国疾病控制与预防中心(Atlanta, GA, USA; www.cdc.gov)的资料，需要使用最小抑制浓度(MIC)来检测金黄色葡萄球菌对万古霉素的耐药性。所有Dade Behring公司的MicroScan检测面板都是以MIC方法为基础，被认为在确定抗微生物药物对抗菌药物的易感性方面是最敏感的方法。迄今为止，已经报道了四种耐万古霉素的金黄色葡萄球菌菌株。根据该公司MicroScan自动检测系统的精确性，Dade Behring一直致力于检测这些菌株。
 
Antimycrobial Susceptibility Testing
 
An improved formulation has been developed for MicroScan dried Gram-positive overnight antimicrobial susceptibility test panels. The new formulation has been cleared by the U.S. Food and Drug Administration (FDA).

Dade Behring (Deerfield, IL, USA) is now offering this automated system for the improved detection of vancomycin-resistant Staphylococcus aureus (VRSA) because of the increasing resistance of S aureus strains.

“Our research team knows how critical this issue is to clinicians and their patients; we understand that vancomycin continues to be a critical antimicrobial agent for treating infections caused by S aureus strains that are resistant to the penicillins and other microbial agents,” explained Barbara Zimmer, Ph.D., director of clinical and scientific affairs, Dade Behring, MicroScan.

According to the U.S. Centers for Disease Control and Prevention (Atlanta, GA, USA; www.cdc.gov), S aureus should be tested for resistance to vancomycin using a minimal inhibitory concentration (MIC) method. All of Dade Behring’s MicroScan testing panels are based on the MIC method, which is considered to be the most sensitive method to determine susceptibility to antimicrobial agents. To date, four strains of vancomycin-resistant S aureus have been reported. Dade Behring has continued to detect these strains due to the accuracy of the company’s MicroScan automated system.