美开展验证基因芯片检测资料可重复性的研究

 
一项最新研究业已证实基因芯片分析得出的高水平基因表达特征是可以重复的，能够在临床应用中进一步推广。

基因芯片质量控制(MAQC)研究是由美国食品药品协会(FDA, Rockville, MD, USA)领导的合作研究。该研究包括来自私立和公立实验室的137位科学家。Affymetrix(Santa Clara, CA, USA)和其他基因芯片和试剂生产厂商参加了为期2年的初始设计，以验证基因芯片检测数据的可重复性。该研究结果报道在2006年9月8日《自然生物技术》之上。
 
Study Determines MicroArray Data Reproducibility
 
A new study has demonstrated that at a high level, gene expression signatures generated by microarrays are repeatable, further advancing the field towards widespread use in clinical applications.

The MicroArray Quality Control (MAQC) study was a collaborative effort led by the U.S. Food and Drug Association (FDA, Rockville, MD, USA). The study included 137 scientists from private and public sector laboratories. Affymetrix (Santa Clara, CA, USA) and other microarray and reagent manufacturers participated in the two-year initiative designed to address the reproducibility of data generated from microarrays. The study’s results were reported in the September 8, 2006, issue of Nature Biotechnology.