严重急性呼吸综合征患者肺部残留

病变CT 远期随访研究
刘长柱 程国英 冯元博 刘月 华琳 彭堃
【摘要】 目的 探讨严重急性呼吸综合征( SARS) 患者肺部残留病变CT 远期动态变化特点及
相关残留因素分析。方法 随访50 例SARS 患者( 男16 例, 女34 例) , 分别于发病后3、6、9、14、24 个
月行螺旋CT 常规扫描和高分辨率扫描。结果 ( 1) 3 个月随访显示24 例肺内残留病变基本吸收,
6 个月吸收30 例, 14 个月35 例, 24 个月37 例, 仍有13 例肺内残留病变, 其中磨玻璃样病灶8 例, 细
网状影4 例, 索条影6 例, 胸膜下弧形影2 例, 合并牵拉性支气管扩张2 例。( 2) 回顾性对比3 个月肺
内病灶残留组与吸收组患者发病不同时期( 3 ～21 d) 胸部影像特点, 显示在病灶大小及进展方面差异
有统计学意义( P < 0. 05) 。( 3) 比较2 个年龄组( ≥40 岁24 例, < 40 岁26 例) 随访不同阶段肺内病
灶残留率, 差异均有统计学意义( P 值均< 0. 05) 。结论 26% ( 13 / 50) SARS 患者于24 个月随访仍
可见肺内病变残留, 病灶仍以磨玻璃样病灶为主( 8 /13) , 并伴有肺间质增生及纤维化; 年龄≥40 岁的
患者, 肺内易残留病变。
【关键词】 严重急性呼吸综合征; 体层摄影术, X 线计算机; 随访研究
Long-term follow-up study for the r emaining lesions of lungs in patients with SARS LIU Changzhu,
CHENG Guo-ying, FENG Yuan-bo, LIU Yue, HUALin, PENG Kun. Depa rtment of Radiology, Beijing
Sixth Hospita l, Beijing 100007, China
【Abstra ct 】 Objective To study the dynamic CT features of severe acute respiratory syndrome
( SARS) in recovery phase, and to analyze the correlative remaining factors on CT images. Methods Total
50 patients with SARS were followed-up with chest spiral CT and HRCT in 3, 6, 9, 14, 24 months after
onset. Results ( 1) The pulmonary lesions were completely absorbed in 24 cases in 3 months, 30 cases in
6 months and 37 cases in 24 months. Abnormal CT findings were showed in 13 patients later, which
appeared ground-glass opacity 8, irregular lines 6, thickening of interlobular septa 4, subpleural lines 2 and
bronchiectasis 2. ( 2) Reviewing the lesions on CT between the remained group in the third month and the
absorption group, there was a difference in the extent and the progress of the lesions . ( 3 ) There was a
difference of the appearance rate of remaining lesion in lungs in two groups ( ≥40 ages and < 40 ages) .
Conclusion ( 1 ) Residual lesions were found in 26. 0% patients with SARS in 24 months after onset ,
which appeared mainly as the ground-glass lesions with pulmonary interstitial hyperplasia and fibrosis . ( 2) If
the progress was rapid and long, the extent of lesions was extensive and ages was more than 40 in their
suffering stage, the pulmonary lesions would be remained frequently.
【Key wor ds 】 Severe acute respiratory syndrome; Tomography, X-ray computed; Follow-up
studies

严重急性呼吸综合征患者肺部残留.rar